产品货号:
Z22702
中文名称:
ORC1抗体
英文名称:
Anti-ORC1 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
| 抗体名称 | Anti-ORC1 Antibody |
| 指标别名 | origin recognition complex subunit 1;HSORC1L;PARC1;ORC1 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB |
| 基因名称 | ORC1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Synthesized peptide derived from the Internal region of human ORC1.at AA rangle:300-380 |
| 计算分子量 | 97KD |
| 成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| 纯化方式 | Immunogen affinity purified |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
| 背景资料 | Origin recognition complex subunit 1 is a protein that in humans is encoded by the ORC1 gene.The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells.Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins.The protein encoded by this gene is the largest subunit of the ORC complex.While other ORC subunits are stable throughout the cell cycle,the levels of this protein vary during the cell cycle,which has been shown to be controlled by ubiquitin-mediated proteolysis after initiation of DNA replication.This protein is found to be selectively phosphorylated during mitosis.It is also reported to interact with MYST histone acetyltransferase 2 (MyST2/HBO1),a protein involved in control of transcription silencing.Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | Q13415 |
| 基因名全称 | Origin recognition complex subunit 1 |
| 推荐稀释比 | WB,1:500~1:2000 |
相关搜索:ORC1抗体,ORC1多抗,Anti-ORC1 Antibody
