产品货号：
Z22645
中文名称：
p21/CDKN1A抗体
英文名称：
Anti-p21/CDKN1A Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-p21/CDKN1A Antibody |
| 指标别名 | CAP20;CDK interacting protein 1;CDKN1;CDKN1A;CIP1;MDA 6;MDA6;P21;p21CIP1;PIC1;SDI1;WAF1 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC/IF,Direct ELISA |
| 基因名称 | CDKN1A |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human P21/CDKN1A recombinant protein (Position:M1-R140). |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | This gene encodes a potent cyclin-dependent kinase inhibitor.The encoded protein binds to and inhibits the activity of cyclin-cyclin-dependent kinase2 or -cyclin-dependent kinase4 complexes,and thus functions as a regulator of cell cycle progression at G1.The expression of this gene is tightly controlled by the tumor suppressor protein p53,through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli.This protein can interact with proliferating cell nuclear antigen,a DNA polymerase accessory factor,and plays a regulatory role in S phase DNA replication and DNA damage repair.This protein was reported to be specifically cleaved by CASP3-like caspases,which thus leads to a dramatic activation of cyclin-dependent kinase2,and may be instrumental in the execution of apoptosis following caspase activation.Mice that lack this gene have the ability to regenerate damaged or missing tissue.Multiple alternatively spliced variants have been found for this gene. |
| Uniprot ID | P38936 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P). |
| 基因名全称 | cyclin dependent kinase inhibitor 1A |
| 蛋白名全称 | Cyclin-dependent kinase inhibitor 1 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Direct ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
| Gene ID | 1026 |
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