产品货号：
Z22481
中文名称：
OPA1抗体
英文名称：
Anti-OPA1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-OPA1 Antibody |
| 指标别名 | KIAA0567;largeG;MGM1;NTG;OPA1;Optic atrophy protein 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,IHC-F,ICC/IF,FCM |
| 基因名称 | OPA1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human OPA1 (919-955aa EDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEA),different from the related mouse and rat sequences by one amino acid. |
| 实际分子量 | 80～100KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Dynamin-like 120kDa protein,mitochondrial is a protein that in humans is encoded by the OPA1 gene.It is mapped to 3q29.This protein regulates mitochondrial fusion and cristae structure in the inner mitochondrial membrane (IMM) and contributes to ATP synthesis and apoptosis.This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases.It is a component of the mitochondrial network.Mutations in this gene have been associated with optic atrophy type 1,which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity,leading in many cases to legal blindness.Multiple transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | O60313 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | optic atrophy 1 (autosomal dominant) |
| 蛋白名全称 | Dynamin-like 120kDa protein,mitochondrial |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunohistochemistry in frozen section (IHC-F) 1:50～400 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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