产品货号：
Z22464
中文名称：
OPG/TNFRSF11B抗体
英文名称：
Anti-OPG/TNFRSF11B Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-OPG/TNFRSF11B Antibody |
| 指标别名 | TNF receptor superfamily member 11b;OCIF;OPG;PDB5;TR1;TNFRSF11B |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat,monkey |
| 应用范围 | WB,IHC,FCM,ELISA |
| 基因名称 | TNFRSF11B |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Osteoprotegerin/TNFRSF11B recombinant protein (Position:Q247-R296). |
| 实际分子量 | 55KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B),also known as OPG,is a protein that in humans is encoded by the TNFRSF11B gene.OPG is a cytokine receptor,and a member of the tumor necrosis factor (TNF) receptor superfamily.By analysis of radiation hybrids,TNFRSF11B gene was mapped to chromosome 8q24.OPG is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL).By binding RANKL,OPG inhibits nuclear kappa B (NF-κB) which is a central and rapid acting transcription factor for immune-related genes,and a key regulator of inflammation,innate immunity,and cell survival and differentiation.OPG binding to RANKL on osteoblast/stromal cells,blocks the RANKL-RANK ligand interaction between osteoblast/stromal cells and ostepclast precursors. |
| Uniprot ID | O00300 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (ELISA)： 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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