产品货号：
Z22440
中文名称：
OAT1/SLC22A6抗体
英文名称：
Anti-OAT1/SLC22A6 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-OAT1/SLC22A6 Antibody |
| 指标别名 | HOAT1;hPAHT;hROAT1;OAT1;Organic anion transporter 1;PAH transporter;PAHT;ROAT1;SLC22A6 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | SLC22A6 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human SLC22A6(534-550aa QKYMVPLQASAQEKNGL),different from the related rat sequence by three amino acids. |
| 实际分子量 | 62KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | SLC22A6(Solute carrier family 22(organic anion transporter),member 6),also called OAT1 or PAHT,is a protein that in humans is encoded by the SLC22A6 gene,which is also a member of the organic anion transporter(OAT) family of proteins.OAT1 is a transmembrane protein that is expressed in the brain,the placenta,the eyes,smooth muscles,and the basolateral membrane of proximal tubular cells of the kidneys.The SLC22A6 gene is mapped on 11q12.3.It plays a central role in renal organic anion transport.Along with OAT3,OAT1 mediates the uptake of a wide range of relatively small and hydrophilic organic anions from plasma into the cytoplasm of the proximal tubular cells of the kidneys.The SLC22A6 gene contains 10 exons and spans 8.2kb.OAT1 functions as organic anion exchanger.When the uptake of one molecule of an organic anion is transported into a cell by an OAT1 exchanger,one molecule of an endogenous dicarboxylic acid(such as glutarate,ketoglutarate,etc) is simultaneously transported out of the cell.PAH uptake in Xenopus oocytes injected with OAT1 mRNA was demonstrated by Race et al. |
| Uniprot ID | Q4U2R8 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1866) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | solute carrier family 22(organic anion transporter),member 6 |
| 蛋白名全称 | Solute carrier family 22 member 6 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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