产品货号：
Z22387
中文名称：
Neuropilin-2/NRP2抗体
英文名称：
Anti-Neuropilin-2/NRP2 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Neuropilin-2/NRP2 Antibody |
| 指标别名 | neuropilin 2;1110048P06Rik;N;Np;Np-2;Np2;Npn-2;Npn2;NRP2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ELISA |
| 基因名称 | NRP2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | The antiserum was produced against synthesized peptide derived from the Internal region of human NRP2 at amino acid range 791-840 |
| 计算分子量 | 105KD |
| 成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| 纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | NRP2(Neuropilin-2),also called Npn2 or VEGF165R2,encodes a member of the neuropilin family of receptor proteins.The soluble NRP2 was secreted as a 62.5-kD protein following transfection in Chinese hamster ovary cells.The NRP2 gene is mapped on 2q33.3.The NRP2 gene contains 17 exons and spans about 112kb.Sema3b can act to repulse axons expressing neuropilin-2 and can antagonize the repulsive action of Sema3a on axonal growth cones expressing neuropilin-1.This protein may play a role in cardiovascular development,axon guidance,and tumorigenesis.Mice with null mutations in genes encoding Sema3F,and its holoreceptor components Npn2 and plexin A3(PLEXA3),exhibit increased dentate gyrus granule cell and cortical layer V pyramidal neuron spine number and size,and also aberrant spine distribution.Moreover,Sema3F promotes loss of spines and excitatory synapses in dissociated neurons in vitro,and in Npn2-null brain slices cortical layer V and dentate gyrus granule cells exhibit increased miniature excitatory postsynaptic current frequency.These disparate effects of secreted semaphorins are reflected in the restricted dendritic localization of Npn2 to apical dendrites and of Npn1 to all dendrites of cortical pyramidal neurons. |
| Uniprot ID | O60462 |
| 基因名全称 | Neuropilin-2 |
| 蛋白名全称 | Neuropilin-2 |
| 推荐稀释比 | WB 1:500～1:2000 IHC-P 1:100～300 ELISA 1:20000 |
相关搜索：Neuropilin-2/NRP2抗体，Neuropilin-2抗体，NRP2多抗，Anti-Neuropilin-2/NRP2 Antibody