产品货号：
Z22279
中文名称：
NR3C2抗体
英文名称：
Anti-NR3C2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NR3C2 Antibody |
| 指标别名 | MCR;Mineralocorticoid receptor;MLR;MR;NR3C2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,ICC/IF |
| 基因名称 | NR3C2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human NR3C2 (950-984aa HALKVEFPAMLVEIISDQLPKVESGNAKPLYFHRK),different from the related mouse sequence by one amino acid,and from the related rat sequence by two amino acids. |
| 实际分子量 | 110KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | NR3C2 (nuclear receptor subfamily 3,group C,member 2),also known as MR (mineralocorticoid receptor),is a protein that in humans is encoded by the NR3C2 gene that is located on chromosome 4q31.1-31.2.It belongs to the nuclear receptor family where the ligand diffuses into cells,interacts with the receptor and results in a signal transduction affecting specific gene expression in the nucleus.This gene encodes the mineralocorticoid receptor,which mediates aldosterone actions on salt and water balance within restricted target cells.The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes.Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I,a disorder characterized by urinary salt wasting.Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy.Alternative splicing results in multiple transcript variants. |
| Uniprot ID | P08235 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | nuclear receptor subfamily 3,group C,member 2 |
| 蛋白名全称 | Mineralocorticoid receptor |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 |
相关搜索：NR3C2抗体，NR3C2多抗，Anti-NR3C2 Antibody