产品货号：
Z22276
中文名称：
NR4A1抗体
英文名称：
Anti-NR4A1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NR4A1 Antibody |
| 指标别名 | Early response protein NAK1;GFRP1;HMR;N10;NAK 1;NAK1;NGFIB;NR4A1;NUR77;Orphan nuclear receptor HMR;Orphan nuclear receptor TR3;ST 59;Testicular receptor 3;TR3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | NR4A1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human NUR77(99-112aa ASFKFEDFQVYGCY),identical to the related rat and mouse sequences. |
| 实际分子量 | 67KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | NR4A1(NUCLEAR RECEPTOR SUBFAMILY 4,GROUP A,MEMBER 1),also called NAK1,GFRP1,TR3,NUR77 or NGFIB,is a protein that in humans is encoded by the NR4A1 gene,which is also a member of the Nur nuclear receptor family of intracellular transcription factors.The NR4A1 gene is mapped on 12q13.13.NR4A1 is involved in cell cycle mediation,inflammation and apoptosis.It plays a key role in mediating inflammatory responses in macrophages.In addition,subcellular localization of the NR4A1 protein appears to play a key role in the survival and death of cells.Nr4a1 was overexpressed in Wnt1 -transformed mouse mammary cells.Nr4a1 was also induced by lithium,a Wnt1 mimic,and the Nr4a1 promoter was activated by lithium and beta-catenin,a Wnt1 downstream effector.In contrast,human NR4A1 was not upregulated by beta-catenin,indicating that this gene is regulated differently in human and mouse cells.Adenoviral expression of Nr4a1 induced genes involved in gluconeogenesis,stimulated glucose production both in vitro and in vivo,and raised blood glucose levels. |
| Uniprot ID | P22736 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | nuclear receptor subfamily 4,group A,member 1 |
| 蛋白名全称 | Nuclear receptor subfamily 4 group A member 1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
相关搜索：NR4A1抗体，NR4A1多抗，Anti-NR4A1 Antibody