产品货号：
Z22241
中文名称：
NKCC2/SLC12A1抗体
英文名称：
Anti-NKCC2/SLC12A1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NKCC2/SLC12A1 Antibody |
| 指标别名 | BSC1;NKCC2;SLC12A1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,monkey,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | SLC12A1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human SLC12A1(52-83aa DEAQKRLRISFRPGNQECYDNFLQSGETAKTD),different from the related mouse sequence by two amino acids,and from the related rat sequence by four amino acids. |
| 实际分子量 | 150～290KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Solute carrier family 12 (sodium/potassium/chloride transporters),member 1,also called NKCC2 is specifically found in cells of the thick ascending limb of the loop of Henle in nephrons,the basic functional units of the kidney.This gene is mapped to 15q21.1.This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa.It plays a key role in concentrating urine and accounts for most of the NaCl resorption.It is sensitive to such diuretics as furosemide and bumetanide.Some Bartter-like syndromes result from defects in this gene.This gene plays a vital role in the regulation of ionic balance and cell volume. |
| Uniprot ID | Q13621 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | solute carrier family 12 (sodium/potassium/chloride transporters),member 1 |
| 蛋白名全称 | Solute carrier family 12 member 1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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