产品货号：
Z22226
中文名称：
NK3R/TACR3抗体
英文名称：
Anti-NK3R/TACR3 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NK3R/TACR3 Antibody |
| 指标别名 | Neuromedin-K receptor;NKR;NK-3 receptor;NK-3R;Neurokinin B receptor;Tachykinin receptor 3;TACR3;NK3R;TAC3R |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | TACR3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | NK3R antibody was raised against a 18 amino acid synthetic peptide from near the center of human NK3R.The immunogen is located within amino acids 370 - 420 of NK3R. |
| 计算分子量 | 52kDa |
| 成分 | NK3R Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | NK3R Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | NK3R antibody can be stored at 4℃ up to one year.Antibodies should not be exposed to prolonged high temperatures. |
| 背景资料 | The tachykinins are a family of small peptides that include the neurotransmitters substance P,neurokinin A,and neurokinin B,which can act on three related but distinct seven transmembrane G-proteins coupled receptors,albeit at different concentrations.The NK-3 receptor (NK3R) has greatest affinity for neurokinin B and is highly expressed in the supraoptic and paraventricular nuclei.Following binding of its ligand,NK3R activates a phosphatidylinositol-calcium second messenger system.It is likely these signals lead to the release of vasopressin and oxytocin into the circulation.NK3R may be involved in learning and memory as mice lacking this gene expressed cognitive deficits compared to normal mice.Although it has been suggested that NK3R plays a role in the regulation of vagal afferent relay neurons,it is likely that these receptors are activated by substance P or neurokinin A,as the airway nerves do not express neurokinin B. |
| Uniprot ID | P29371 |
| 基因名全称 | Tachykinin receptor 3 |
| 蛋白名全称 | Tachykinin receptor 3 |
| 推荐稀释比 | NK3R antibody can be used for detection of NK3R by Western blot at 0.5 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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