产品货号:
Z22179
中文名称:
NOXA1抗体
英文名称:
Anti-NOXA1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-NOXA1 Antibody |
指标别名 | NADPH oxidase activator 1;NY-CO-31;SDCCAG31;p51NOX;NOXA1 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB |
基因名称 | NOXA1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human NOXA1(176-195aa RQVPRGEVFRPHRWHLKHLE). |
实际分子量 | 51KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | NOXA1(NADPH oxidase activator 1),also called NOX ACTIVATOR 1 or p51-NOX,is an enzyme that in humans is encoded by the NOXA1 gene.Hartz(2007) mapped the NOXA1 gene to chromosome 9q34.3 based on an alignment of the NOXA1 sequence with the genomic sequence(build 36.1).Banfi et al.(2003) mapped the mouse Noxa1 gene to chromosome 2.Using yeast 2-hybrid assays,Takeya et al.(2003) showed that human p51-NOX interacted with constitutively active forms of RAC1 and RAC2.In vitro binding assays revealed that p51-NOX bound GTP-bound RAC1,but not GDP-bound RAC1.p51-NOX also bound p47-PHOX(NCF1) and p41-NOX(NOXO1),and trp436 within the SH3 domain of p51-NOX was required for these interactions.Human cell lines or COS-7 cells cotransfected with p51-NOX and p41-NOX and either gp91-PHOX(CYBB) or NOX1 produced superoxide.Cells individually transfected with NOX1,p41-NOX,or p51-NOX and cells transfected with only p41-NOX and p51-NOX showed no superoxide production. |
Uniprot ID | Q86UR1 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | NADPH oxidase activator 1 |
蛋白名全称 | NADPH oxidase activator 1 |
推荐稀释比 | Western blot(WB) 1:500~2000 |
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