产品货号:
Z22145
中文名称:
NLRP1抗体
英文名称:
Anti-NLRP1 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
| 抗体名称 | Anti-NLRP1 Antibody |
| 指标别名 | CARD7;CLR17.1;DEFCAP;DEFCAP L/S;KIAA0926;NAC;NALP1;NLRP1;PP1044;SLEV1;VAMAS1 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | NLRP1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | NALP1 antibody was raised against a peptide corresponding to 13 amino acids near the carboxy terminus of human NALP1.The immunogen is located within the last 50 amino acids of NALP1. |
| 计算分子量 | 166kDa |
| 成分 | NALP1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | NALP1 Antibody is immunoaffinity chromatography purified IgG. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
| 背景资料 | NALP1 belongs to a family of cytoplasmic proteins that have been implicated in cell responses to apoptotic and inflammatory stimuli.It contains a caspase recruitment domain (CARD) in addition to a NACHT domain and leucine rich repeat (LRR).This protein interacts strongly with caspase 2 and weakly with caspase 9,as well as with Apaf-1.Transient overexpression of this gene in cultured cells was sufficient to induce apoptosis.NALP1 mRNA and protein expression levels in myeloid leukemia cells are increased following CREB (cAMP-response element binding protein) activation,suggesting that NALP1 may contribute to modulate the response of these cells to pro-inflammatory stimuli.Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for NALP1. |
| Uniprot ID | Q9C000 |
| 基因名全称 | NLR family,pyrin domain containing 1 |
| 蛋白名全称 | NLR family,pyrin domain containing 1 |
| 推荐稀释比 | NALP1 antibody can be used for detection of NALP1 by Western blot at 1 to 4μg/mL.Antibody can also be used for immunocytochemistry starting at 10μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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