产品货号:
Z22129
中文名称:
NUDT5抗体
英文名称:
Anti-NUDT5 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
| 抗体名称 | Anti-NUDT5 Antibody |
| 指标别名 | NUDT5;NUDIX5;HSPC115;ADP-sugar pyrophosphatase;8-oxo-dGDP phosphatase;Nuclear ATP-synthesis protein NUDIX5;Nucleoside diphosphate-linked moiety X motif 5;Nudix motif 5;hNUDT5;YSA1H |
| 克隆性 | Polyclonal |
| 检验物种 | human,rat |
| 应用范围 | WB,IHC,FCM(Intracellular),ELISA |
| 基因名称 | NUDT5 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human NUDT5 recombinant protein (Position:M1-F219). |
| 实际分子量 | 35KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | ADP-sugar pyrophosphatase is an enzyme that in humans is encoded by the NUDT5 gene.This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily.The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates,including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP.Protein-bound ADP ribose can be hazardous to the cell because it can modify some amino acid residues,resulting in the inhibition of ATP-activated potassium channels.8-oxoGua is an oxidized form of guanine that can potentially alter genetic information by pairing with adenine and cytosine in RNA.Presence of 8-oxoGua in RNA results in formation of abnormal proteins due to translational errors. |
| Uniprot ID | Q9UKK9 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P). |
| 基因名全称 | nudix hydrolase 5 |
| 蛋白名全称 | ADP-sugar pyrophosphatase |
| 推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:50~400 Flow Cytometry(Intracellular) 1~3μg/1×106 cells ELISA 1:100~1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
| Gene ID | 11164 |
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