产品货号：
Z22122
中文名称：
NUMB抗体
英文名称：
Anti-NUMB Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NUMB Antibody |
| 指标别名 | h Numb;NUMB;numb homolog (Drosophila);Protein numb homolog;Protein S171;S171 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | NUMB |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | NUMB antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human NUMB.The immunogen is located within the last 50 amino acids of NUMB. |
| 计算分子量 | 71kDa |
| 成分 | NUMB Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | NUMB Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | NUMB,the mammalian homolog to the Drosophila asymmetric cell fate determinant NUMB,is thought to share several features molecular mechanisms in mammalian cells,generating asymmetric cell divisions during neurogenesis in vertebrate development as well as in hematopoietic stem cells.NUMB has been shown to inhibit Notch signaling,and is itself regulated by ubiquitinylation by MDM2.NUMB has also been shown to help activate the tumor suppressor p53,suggesting that loss of NUMB in cancerous cells would not only activate the potential oncogene Notch,but diminish the tumor suppressing effect of p53. |
| Uniprot ID | P49757 |
| 基因名全称 | Numb homolog (Drosophila) |
| 蛋白名全称 | Numb homolog (Drosophila) |
| 推荐稀释比 | NUMB antibody can be used for detection of NUMB by Western blot at 0.25 ～ 0.5μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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