产品货号：
Z22058
中文名称：
NF-κB p65/RELA抗体
英文名称：
Anti-NF-κB p65/RELA Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NF-κB p65/RELA Antibody |
| 指标别名 | NF Kappa B;NF κB;NFKB 3;NFKB p65;NFKB3;NF-κB;NF-κB3;p65;RELA;Transcription factor p65 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC |
| 基因名称 | RELA |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human NF-kB p65(143-158aa VPIEEQRGDYDLNAVR),identical to the related rat and mouse sequences. |
| 实际分子量 | 65KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | RELA(V-REL AVIAN RETICULOENDOTHELIOSIS VIRAL ONCOGENE HOMOLOG A),also called NFKB3 or NFKB,p65 SUBUNIT.NFKB1 or NFKB2 is bound to REL,RELA,or RELB to form the NFKB complex.The NFKB complex is inhibited by I-kappa-B proteins,which inactivate NFKB by trapping it in the cytoplasm.The p65(RELA) heterodimer is the most abundant form of NFKB.And the RELA gene is located on 11q13.1.RELA is a nonhistone substrate of HDAC3 and that IKBA-dependent nuclear export of the HDAC3-deacetylated RELA replenishes the depleted cytoplasmic pool of latent NFKB-IKBA complexes for subsequent NFKB responses.RELA nucleocytoplasmic redistribution coincided with export of PPARG,and immunoprecipitation analysis indicated that PPARG-RELA association was dependent on the PPARG C-terminal ligand-binding domain.IKK-dependent phosphorylation of RELA on ser468 enhanced binding of GCN5 to RELA and RELA ubiquitination. |
| Uniprot ID | Q04206 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | v-rel reticuloendotheliosis viral oncogene homolog A(avian) |
| 蛋白名全称 | Transcription factor p65 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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