产品货号：
Z22047
中文名称：
NFATC1抗体
英文名称：
Anti-NFATC1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NFATC1 Antibody |
| 指标别名 | nuclear factor of activated T cells 1;NF-ATC;NF-ATc1.2;NFAT2;NFATc;NFATC1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC-F,ICC,FCM,ELISA |
| 基因名称 | NFATC1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human NFAT2 recombinant protein (Position:Q589-K652). |
| 实际分子量 | 101KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | NFATC1(Nuclear factor of activated T-cells,cytoplasmic 1),also known as NFATC or NFAT2,is a protein that in humans is encoded by the NFATC1 gene.And it is also a component of the nuclear factor of activated T cells DNA-binding transcription complex.The NFATC1 gene is mapped on 18q23.Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response.NFATC1 was not detected in brain,liver,or kidney.NFATC1 is an inducible nuclear component which functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A.The solution structure of the binary complex formed between the core DNA-binding domain of human NFATC1 and the 12-bp oligonucleotide duplex containing the ARRE2 DNA site from the IL2 promoter.Nfatc1 was expressed exclusively in mouse hair follicle stem cells,and using gain- and loss-of-function approaches,and Nfatc1 inhibited stem cell activation. |
| Uniprot ID | O95644 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in frozen section 1:50～400 Immunocytochemistry in fixed cells 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (ELISA)： 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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