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产品目录

Nephrin/NPHS1抗体图片
产品货号:
Z22023
中文名称:
Nephrin/NPHS1抗体
英文名称:
Anti-Nephrin/NPHS1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-Nephrin/NPHS1 Antibody
指标别名NPHS1adhesion molecule;nephrin;CNF;NPHN;nephrin
克隆性Polyclonal
检验物种human,mouse,rat
应用范围WB,IHC
基因名称NPHS1
抗体来源Rabbit
抗体类型IgG
免疫原E.coli-derived human Nephrin recombinant protein (Position:V1084-V1241).Human Nephrin shares 79.9% and 75.3% amino acid (aa) sequence identity with mouse and rat Nephrin,respectively.
实际分子量135KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料NPHS1,also called Nephrin,is mapped to 19q13.12.This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney.It gene is primarily expressed in renal tissues,and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes.The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine.A defect in the gene for nephrin,NPHS1,is associated with congenital nephrotic syndrome of the Finnish type and causes massive amounts of protein to be leaked into the urine,orproteinuria.NPHS1 is also required for cardiovascular development.
Uniprot IDO60500
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
推荐稀释比
Western blot (WB) 1:500~2000
Immunohistochemistry in paraffin section (IHC) 1:50~400
(Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user.

相关搜索:Nephrin/NPHS1抗体Nephrin抗体NPHS1多抗Anti-Nephrin/NPHS1 Antibody
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