产品货号：
Z22011
中文名称：
NOD3/NLRC3抗体
英文名称：
Anti-NOD3/NLRC3 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NOD3/NLRC3 Antibody |
| 指标别名 | NOD3,CLR16.2,NOD3,Protein NLRC3,CARD15-like protein |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IF |
| 基因名称 | NLRC3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | NOD3 antibody was raised against an 18 amino acid synthetic peptide near the center of human NOD3.The immunogen is located within amino acids 630 - 680 of NOD3. |
| 计算分子量 | 115kDa |
| 成分 | NOD3 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | NOD3 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | NOD3 is a member of the NOD (nucleotide-binding oligomerization domain) family,a group of proteins that are involved in innate immune defense.NOD3 also known as NLR family CARD containing 3 (NLRC3),is predominantly expressed in the immune system,particularly in T lymphocytes,and its expression is strongly down-regulated following stimulation of the T-cell receptor complex and CD28,suggesting that NOD3 plays a role in attenuating the activation of T cells.NOD3 inhibits NF-kappaB,AP-1 and NFAT transcriptional activation in Jurkat T cells downstream of CD3/CD28 stimulation or treatment with PMA/ionomycin and decreases IL-2 and CD25 mRNA induction in activated cells. |
| Uniprot ID | Q7RTR2 |
| 基因名全称 | NLR family,CARD domain containing 3 |
| 蛋白名全称 | NLR family,CARD domain containing 3 |
| 推荐稀释比 | NOD3 antibody can be used for detection of NOD3 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunofluorescence starting at 20μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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