产品货号：
Z21861
中文名称：
NR1H3抗体
英文名称：
Anti-NR1H3 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NR1H3 Antibody |
| 指标别名 | Liver X receptor alpha;LXR a;LXRA;LXRα;NR1H3;Oxysterols receptor LXR alpha;RLD 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | NR1H3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human LXR alpha(371-385aa NVQDQLQVERLQHTY),identical to the related rat and mouse sequences. |
| 实际分子量 | 51KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | LXRA is a tissue-specific cofactor that permits RXRA to function as a potent 9cRA receptor with a distinct target gene specificity.It specifically interacts with RXRA in vivo to form a functional heterodimer in which RXRA is the ligand-binding subunit.Additionally,LXR activity is critical for physiologic lipid metabolism and transport.LXRs are endogenous inhibitors of atherogenesis and are targets for therapeutic intervention in cardiovascular disease.Furthermore,LXRs and their ligands are negative regulators of macrophage inflammatory gene expression.LXR is also found that as a transcriptional switch that integrates hepatic glucose metabolism and fatty acid synthesis.The LXR-IDOL-LDLR axis defines a complementary pathway to sterol response element-binding proteins for sterol regulation of cholesterol uptake. |
| Uniprot ID | Q13133 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | nuclear receptor subfamily 1,group H,member 3 |
| 蛋白名全称 | Oxysterols receptor LXR-alpha |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
相关搜索：NR1H3抗体，NR1H3多抗，Anti-NR1H3 Antibody