产品货号：
Z21819
中文名称：
NPHS2抗体
英文名称：
Anti-NPHS2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NPHS2 Antibody |
| 指标别名 | NPHS2;PDCN;Podocin;SRN1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | NPHS2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human NPHS2(126-143aa CVKVVQEYERVIIFRLGH),different from the mouse sequence by one amino acid. |
| 实际分子量 | 42KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Podocin(PDCN) is a protein which lines the podocytes and assists in maintaining the barrier at the glomerular basement membrane.NPHS2 is a causative gene for Familial idiopathic nephrotic syndromes,which represents a heterogeneous group of kidney disorders,and include autosomal recessive steroid-resistant nephrotic syndrome,which is characterized by early childhood onset of proteinuria,rapid progression to end-stage renal disease and focal segmental glomerulosclerosis.By positional cloning,NPHS2 was mapped to 1q25-31.It is almost exclusively expressed in the podocytes of fetal and mature kidney glomeruli,and encodes a new integral membrane protein,podocin,belonging to the stomatin protein family.Boute et al.(2000) found ten different NPHS2 mutations,comprising nonsense,frameshift and missense mutations,to segregate with the disease,demonstrating a crucial role for podocin in the function of the glomerular filtration barrier. |
| Uniprot ID | Q9NP85 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | nephrosis 2,idiopathic,steroid-resistant(podocin) |
| 蛋白名全称 | Podocin |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
相关搜索：NPHS2抗体，NPHS2多抗，Anti-NPHS2 Antibody