产品货号:
Z21673
中文名称:
NALP5抗体
英文名称:
Anti-NALP5 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-NALP5 Antibody |
指标别名 | MATER,NALP5,PAN11,PYPAF8,CLR19.8,MATER,NACHT,LRR and PYD domains-containing protein 5,Mater protein homolog |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | NLRP5 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | NALP5 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human NALP5.The immunogen is located within the last 50 amino acids of NALP5. |
计算分子量 | 134kDa |
成分 | NALP5 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | NALP5 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction.NALP5,also known as MATER,is a maternal gene required for early embryonic development in mice.Increased NALP5 expression was observed in two neuronal injury models,and transient expression of recombinant NALP5 in neurons induced caspase-3 activation and apoptosis,suggesting that NALP5 also plays a role in caspase activation and apoptosis in injured neurons,and may thus represent a novel target for therapeutic treatment in neurodegenerative disorders. |
Uniprot ID | P59047 |
基因名全称 | NLR family,pyrin domain containing 5 |
蛋白名全称 | NLR family,pyrin domain containing 5 |
推荐稀释比 | NALP5 antibody can be used for detection of NALP5 by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 10μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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