产品货号：
Z21541
中文名称：
NCOA1抗体
英文名称：
Anti-NCOA1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NCOA1 Antibody |
| 指标别名 | nuclear receptor coactivator 1;F-SRC-1;KAT13A;RIP160;SRC1;bHLHe42;bHLHe74;NCOA1 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,ICC/IF,FCM |
| 基因名称 | NCOA1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human KAT13A recombinant protein (Position:H614-Q826).Human KAT13A shares 92% amino acid (aa) sequence identity with mouse KAT13A. |
| 实际分子量 | 157KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | The nuclear receptor coactivator 1 (NCOA1),also known as SRC1,is a transcriptional coregulatory protein that contains several nuclear receptor interacting domains and an intrinsic histone acetyltransferase activity.NCOA1 is recruited to DNA promotion sites by ligand-activated nuclear receptors.NCOA1,in turn,acylates histones,which makes downsteam DNA more accessible to transcription.Hence,NCOA1 assists nuclear receptors in the upregulation of DNA expression.It has been found that NCOA1 can enhance the transcriptional activity of ligand-bound PGR but does not alter the basal activity of the target promoter.It also enhances estrogen receptor,glucocorticoid receptor,thyroid hormone receptor,and retinoid X receptor transcriptional activities through their cognate DNA response elements in the presence of hormone.What’s more,SRC1 may play a role as a bridging molecule between nuclear hormone receptors and general transcription factors. |
| Uniprot ID | Q15788 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | nuclear receptor coactivator 1 |
| 蛋白名全称 | Nuclear receptor coactivator 1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells |
相关搜索：NCOA1抗体，NCOA1多抗，Anti-NCOA1 Antibody