产品货号：
Z21525
中文名称：
NCOA1抗体
英文名称：
Anti-NCOA1 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NCOA1 Antibody |
| 指标别名 | nuclear receptor coactivator 1;F-SRC-1;KAT13A;RIP160;SRC1;bHLHe42;bHLHe74;NCOA1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,ELISA |
| 基因名称 | NCOA1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Synthesized peptide derived from human NCOA1 protein. |
| 计算分子量 | 157KD |
| 成分 | Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide. |
| 纯化方式 | NCOA1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | The nuclear receptor coactivator 1 (NCOA1),also known as SRC1,is a transcriptional coregulatory protein that contains several nuclear receptor interacting domains and an intrinsic histone acetyltransferase activity.NCOA1 is recruited to DNA promotion sites by ligand-activated nuclear receptors.NCOA1,in turn,acylates histones,which makes downsteam DNA more accessible to transcription.Hence,NCOA1 assists nuclear receptors in the upregulation of DNA expression.It has been found that NCOA1 can enhance the transcriptional activity of ligand-bound PGR but does not alter the basal activity of the target promoter.It also enhances estrogen receptor,glucocorticoid receptor,thyroid hormone receptor,and retinoid X receptor transcriptional activities through their cognate DNA response elements in the presence of hormone.What’s more,SRC1 may play a role as a bridging molecule between nuclear hormone receptors and general transcription factors. |
| Uniprot ID | Q15788 |
| 基因名全称 | Nuclear receptor coactivator 1 |
| 蛋白名全称 | Nuclear receptor coactivator 1 |
| 推荐稀释比 | WB 1:500～2000 ELISA 1:5000～20000 |
相关搜索：NCOA1抗体，NCOA1多抗，Anti-NCOA1 Antibody