产品货号：
Z21488
中文名称：
Myosin/MYL12A抗体
英文名称：
Anti-Myosin/MYL12A Antibody
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Myosin/MYL12A Antibody |
| 指标别名 | MLC 2B;MLCB;MRLC3;MYL12A;MYL2B;Myosin RLC;RLC |
| 克隆性 | Polyclonal |
| 检验物种 | mouse,rat |
| 应用范围 | ELISA,WB |
| 基因名称 | MYL12A |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids aa 10-35 of human myosin light chain protein. |
| 计算分子量 | 20kDa |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | This affinity purified antibody is directed against the regulatory light chain of smooth and non-muscle myosin.The antibody detects both unphosphorylated and monophosphorylated forms of the protein.The product was affinity purified from monospecific antiserum by immunoaffinity purification.Cross-reactivity is expected with myosin light chain from human,mouse and rat sources.Reactivity with the protein from other species has not been determined;however,the sequence of the immunogen is nearly identical in mammalian and avian species.BLAST search analysis was used to determine that the smooth and non-muscle forms of myosin regulatory light chain have identical sequences.Cross-reactivity is expected. |
| 浓度 | 0.98mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | Myosin is the major component of thick muscle filaments,and is a long asymmetric molecule containing a globular head and a long tail.The molecule consists of two heavy chains each~200,000 daltons,and four light chains each~16,000 - 21,000 daltons.Activation of smooth and cardiac muscle primarily involves pathways that increase calcium and myosin phosphorylation resulting in contraction.Myosin light chain phosphatase acts to regulate muscle contraction by dephosphorylating activated myosin light chain.The selected peptide sequence used to generate the polyclonal antibody is located near the amino terminal end of the polypeptide corresponding to the smooth/non-muscle form of myosin regulatory light chain found in cardiac myocytes in addition to smooth and non-muscle cells. |
| Uniprot ID | J3QRS3 |
| 基因名全称 | Myosin regulatory light polypeptide 9 |
| 推荐稀释比 | ELISA:1:10,000 - 1:70,000 IHC:User Optimized IP:1:100 WB:1:500 - 1:2,000 |
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