
产品货号:
Z21410
中文名称:
MT-CO1抗体
英文名称:
Anti-MT-CO1 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-MT-CO1 Antibody |
指标别名 | mitochondrially encoded cytochrome c oxidase;COI;MTCO1;COX1 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | ELISA,WB |
基因名称 | MT-CO1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from human COX1 protein. |
计算分子量 | 57KD |
成分 | Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide. |
纯化方式 | COX1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | Cytochrome c oxidase subunit I(CO1 or MTCO1) is 1 of 3 mitochondrial DNA(mtDNA) encoded subunits(MTCO1,MTCO2,MTCO3) of respiratory Complex IV.Complex IV is located within the mitochondrial inner membrane and is the third and final enzyme of the electron transport chain of mitochondrial oxidative phosphorylation.It is composed of 13 polypeptides.Subunits I,II,and III(MTCO1,MTCO2,MTCO3) are encoded by mtDNA while subunits IV,Va,Vb,VIa,VIb,VIc,VIIa,VIIb,VIIc,and VIII are nuclear encoded.The cytochrome c oxidase family of enzymes have 4 redox centers,2 hemes and 2 copper centers.In mitochondrial Complex IV,the 2 hemes are a and a3 and the 2 coppers are CuA and CuB.The 2 hemes and CuB are bound to subunit I.Acin-Perez et al.(2003) identified a cell line containing single and double missense mutations in the cytochrome c oxidase(COX) subunit I gene of mouse mitochondrial DNA.And they hypothesized that deleterious mutations can arise and become predominant;cultured cells can maintain several mtDNA haplotypes at stable frequencies;the respiratory chain has little spare COX capacity;and that the size of a cavity in the vicinity of val421 in MTCO1I of animal COX may affect the function of the enzyme. |
Uniprot ID | P00395 |
基因名全称 | Cytochrome c oxidase subunit 1 |
蛋白名全称 | Cytochrome c oxidase subunit 1 |
推荐稀释比 | WB 1:500~2000 ELISA 1:5000~20000 |
相关搜索:MT-CO1抗体,MT-CO1多抗,Anti-MT-CO1 Antibody