产品货号:
Z21308
中文名称:
NANOS1抗体
英文名称:
Anti-NANOS1 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-NANOS1 Antibody |
指标别名 | NOS1;SPGF12;NOS1;Nanos homolog 1;NOS-1 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | NANOS1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Nanos1 antibody was raised against a 17 amino acid synthetic peptide from near the amino terminus of human Nanos1.The immunogen is located within the first 50 amino acids of Nanos1. |
计算分子量 | 30kDa |
成分 | Nanos1 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | Nanos1 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Nanos1 is one of three known mammalian homologs to the Drosophila gene nanos.Nanos1 is an RNA-binding protein containing a zinc-finger motif and is expressed in the developing nervous system and continues in the adult brain.Interestingly,unlike mice deficient in either nanos2 or nanos3,mice lacking the nanos1 gene develop normally with no sign of abnormalities.Recently it has been found that expression of nanos1 mRNA is down-regulated by E-cadherin in a human breast cancer cell line and the amino-terminal domain on Nanos1 interacts with the E-cadherin-binding protein p120ctn.Furthermore,overexpression of Nanos1 in human colorectal DLD1 cancer cells functionally abolished cell-cell adhesion,allowing the cancer cells to develop strong migratory and invasive properties.These results suggest that targeting Nanos1 might prove an effective strategy in the treatment of E-cadherin-negative tumors. |
Uniprot ID | Q8WY41 |
基因名全称 | Nanos homolog 1 (Drosophila) |
蛋白名全称 | Nanos homolog 1 (Drosophila) |
推荐稀释比 | Nanos1 antibody can be used for detection of Nanos1 by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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