产品货号：
Z21069
中文名称：
MSI2抗体
英文名称：
Anti-MSI2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MSI2 Antibody |
| 指标别名 | MSI2;MSI2H;Musashi 2;musashi homolog 2 (Drosophila) |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC,IHC,IF |
| 基因名称 | MSI2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | MSI2 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human MSI2.The immunogen is located within amino acids 30 - 80 of MSI2. |
| 计算分子量 | 35kDa |
| 成分 | MSI2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | MSI2 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | MSI2 antibody can be stored at 4℃,stable for one year.As with all antibodies care should be taken to avoid repeated freeze thaw cycles.Antibodies should not be exposed to prolonged high temperatures. |
| 背景资料 | Musashi2 (MSI2) is an RNA-binding protein that is highly expressed in precursor cells in the ventricular and subventricular zones of the developing mammalian CNS.Like the related MSI1,MSI2 has been suggested to be involved stem cell production and maintenance.MSI2 is the predominant MSI protein in hematopoietic stem cells,and its knockdown leads to reduced engraftment and depletion in vivo.Expression levels of MSI2 are elevated in myeloid leukemia cells lines,and MSI2 appears to cooperate with BCR-ABL1 to induce an aggressive leukemia;the level of MSI2 directly correlates with decreased survival in patients.MSI2 negatively regulates the asymmetric cell fate determinant NUMB,suggesting that this signaling pathway may provide future targets for future therapies. |
| Uniprot ID | Q96DH6 |
| 基因名全称 | Musashi homolog 2 (Drosophila) |
| 蛋白名全称 | Musashi homolog 2 (Drosophila) |
| 推荐稀释比 | MSI2 antibody can be used for detection of MSI2 by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL and immunocytochemistry starting at 5μg/mL.For immunofluorescence start at 5μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in mouse samples;Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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