产品货号：
Z21045
中文名称：
MRP5/ABCC5抗体
英文名称：
Anti-MRP5/ABCC5 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MRP5/ABCC5 Antibody |
| 指标别名 | ABC33;ABCC5;MOAT C;MOATC;MRP5;pABC11;SMRP |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | IHC,FCM,ELISA |
| 基因名称 | ABCC5 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human MRP5/ABCC5 recombinant protein (Position:K647-D1409). |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Multidrug resistance-associated protein 5 is a protein that in humans is encoded by the ABCC5 gene.The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.ABC proteins transport various molecules across extra- and intra-cellular membranes.ABC genes are divided into seven distinct subfamilies (ABC1,MDR/TAP,MRP,ALD,OABP,GCN20,White).This protein is a member of the MRP subfamily which is involved in multi-drug resistance.This protein functions in the cellular export of its substrate,cyclic nucleotides.This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides.Studies show that this protein provides resistance to thiopurine anticancer drugs,6-mercatopurine and thioguanine,and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine.This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients.Alternative splicing results in multiple transcript variants. |
| Uniprot ID | O15440 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | ATP binding cassette subfamily C member 5 |
| 蛋白名全称 | Multidrug resistance-associated protein 5 |
| 推荐稀释比 | Immunohistochemistry in paraffin section IHC 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 |
相关搜索：MRP5/ABCC5抗体，MRP5抗体，ABCC5多抗，Anti-MRP5/ABCC5 Antibody