产品货号：
Z21039
中文名称：
MMP7抗体
英文名称：
Anti-MMP7 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MMP7 Antibody |
| 指标别名 | Matrilysin;Matrin;Matrix metalloproteinase 7;MMP 7;MMP7;MPSL1;PUMP 1;Pump 1 protease;PUMP1;Uterine metalloproteinase |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ELISA |
| 基因名称 | MMP7 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human MMP7 recombinant protein (Position:M1-K267).Human MMP7 shares 71% amino acid (aa) sequences identity with both mouse and rat MMP7. |
| 实际分子量 | 30KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Matrix metalloproteinase-7 (MMP-7) previously called putative metalloproteinase I (PUMP1) or matrilysin.The MMP-7 gene has been identified through studies of collagenase-related connective-tissue-degrading metalloproteinases produced by human tumors.The MMP-7 protein has 267 amino acids and is significantly shorter than stromelysin or collagenase (477 and 469 amino acids,respectively).Matrix metalloproteinases play a crucial role in tumor invasion and metastasis.MMP-7,a member of the matrix metalloproteinase family,is structurally different from the other matrix metalloproteinases by virtue of the absence of a conserved COOH-terminal protein domain.In addition,MMP-7 mRNA is regulated in a specific and distinct manner in normal and malignant tissues.MMP-7 has been shown to correlate with nodal or distant metastasis in colorectal carcinomas,however,its implication in early invasive colorectal carcinomas has not been determined.MMP-7 is also a mediator of pulmonary fibrosis and a potential therapeutic target.The standard product used in this kit is recombinant human MMP-7,consisting of 250 amino acids with the molecular mass of 28KDa.The detected MMP-7 includes zymogen and active enzyme. |
| Uniprot ID | P09237 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | matrix metallopeptidase 7 (matrilysin,uterine) |
| 蛋白名全称 | Matrilysin |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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