产品货号:
Z21019
中文名称:
MESDC2/MESD抗体
英文名称:
Anti-MESDC2/MESD Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-MESDC2/MESD Antibody |
指标别名 | BOCA;KIAA0081;LDLR chaperone MESD;MESD;MESDC2;Mesoderm development protein |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB,FCM,ELISA |
基因名称 | MESD |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human MESDC2/MESD recombinant protein (Position:D80-Q205). |
实际分子量 | 24KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Mesoderm development candidate genes 1 (MESDC1) and 2 (MESDC2) were identified from the mesoderm development (MESD) deletion interval located on mouse chromosome 7.MESD acts as a chaperone for low-density lipoprotein receptor (LDLR) proteins in the ER,and particularly associates with Wnt signaling pathway coreceptors LRP5 and LPR6.MESD is required for proper LRP5/6 folding and maturation to the cell surface,which plays a major role in Wnt signaling.The interaction between MESD and LRP5 is disrupted by a G171V mutation in LRP5 that is found in individuals with a familial phenotype characterized by high bone mass. |
Uniprot ID | Q14696 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
基因名全称 | mesoderm development LRP chaperone |
蛋白名全称 | LRP chaperone MESD |
推荐稀释比 | Western blot(WB) 1:500~2000 Flow cytometry (FCM) 1~3μg/1×106 cells ELISA 1:100~1000 |
相关搜索:MESDC2/MESD抗体,MESDC2抗体,MESD多抗,Anti-MESDC2/MESD Antibody