产品货号：
Z21006
中文名称：
MER/MERTK抗体
英文名称：
Anti-MER/MERTK Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MER/MERTK Antibody |
| 指标别名 | MER proto-oncogene;tyrosine kinase;MER;RP38;Tyro12;c-Eyk;c-mer;MERTK |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,FCM,ELISA |
| 基因名称 | MERTK |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human MERTK recombinant protein (Position:A21-A489). |
| 实际分子量 | 120KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Proto-oncogene tyrosine-protein kinase MER,also called MERTK is an enzyme that in humans is encoded by the MERTK gene.This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains,two Ig-like C2-type(immunoglobulin-like) domains,and one tyrosine kinase domain.This gene is mapped to 2q13.MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells,platelet aggregation,cytoskeleton reorganization and engulfment.This gene is also very important in inhibition of Toll-like receptors(TLRs)-mediated innate immune response by activating STAT1,which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3. |
| Uniprot ID | Q12866 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | MER proto-oncogene,tyrosine kinase |
| 蛋白名全称 | Tyrosine-protein kinase Mer |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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