产品货号:
Z20981
中文名称:
MORG1/WDR83抗体
英文名称:
Anti-MORG1/WDR83 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
| 抗体名称 | Anti-MORG1/WDR83 Antibody |
| 指标别名 | MAPK organizer 1;MORG1;WDR83 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | WDR83 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human Morg1(29-43aa RAVRFNVDGNYCLTC),identical to the related mouse and rat sequences. |
| 实际分子量 | 34KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | MORG1(mitogen-activated protein kinase organizer 1),a member of the WD-40 protein family that was isolated as a binding partner of the extracellular signal-regulated kinase(ERK) pathway scaffold protein MP1.MORG1 specifically associates with several components of the ERK pathway,including MP1,Raf-1,MEK,and ERK,and stabilizes their assembly into an oligomeric complex.MORG1 facilitates ERK activation when cells are stimulated with lysophosphatidic acid,phorbol 12-myristate 13-acetate,or serum,but not in response to epidermal growth factor.Suppression of MORG1 by short interfering RNA leads to a marked reduction in ERK activity when cells are stimulated with serum.MORG1 is a component of a modular scaffold system that participates in the regulation of agonist-specific ERK signaling. |
| Uniprot ID | Q9BRX9 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1866) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | WD repeat domain 83 |
| 蛋白名全称 | WD repeat domain-containing protein 83 |
| 推荐稀释比 | Western blot(WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:50~400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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