产品货号:
Z20823
中文名称:
MUM1/IRF4抗体
英文名称:
Anti-MUM1/IRF4 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-MUM1/IRF4 Antibody |
指标别名 | IRF 4;IRF4;LSIRF;Multiple myeloma oncogene 1;MUM1;MUM1/IRF4;NF EM5 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | WB,IHC,IF,ELISA |
基因名称 | IRF4 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from human IRF-4 |
计算分子量 | 52KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | Interferon regulatory factor 4 (IRF4),also known as MUM1,is a protein that in humans is encoded by the IRF4 gene.It is located on 6p25.3.IRF4 is a transcription factor,and it is essential for the development of T helper-2 (Th2) cells,IL17 -producing Th17 cells,and IL9 -producing Th9 cells.In melanocytic cells,the IRF4 gene may be regulated by MITF.IRF4 is a transcription factor that has been implicated in acute leukemia.This gene is strongly associated with pigmentation,sensitivity of skin to sun exposure,freckles,blue eyes,and brown hair color.What's more,IRF4 inhibition is toxic to myeloma cell lines,regardless of transforming oncogenic mechanism. |
Uniprot ID | Q15306 |
基因名全称 | Interferon regulatory factor 4 |
蛋白名全称 | Interferon regulatory factor 4 |
推荐稀释比 | WB 1:500~1:2000 IHC 1:100~1:300 IF 1:200~1:1000 ELISA 1:20000 |
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