产品货号：
Z20570
中文名称：
MED28抗体
英文名称：
Anti-MED28 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MED28 Antibody |
| 指标别名 | 1500003D12Rik;EG1;Endothelial derived protein 1;magicin;MED28;mediator complex subunit 28;Tumor angiogenesis marker EG 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,IHC |
| 基因名称 | MED28 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | MED28 antibody was raised against a 17 amino acid synthetic peptide from near the center of human MED28.The immunogen is located within amino acids 50 - 100 of MED28. |
| 计算分子量 | 20kDa |
| 成分 | MED28 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | MED28 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The mediator complex is a multi-protein transcriptional co-activator that is expressed ubiquitously in eukaryotes from yeast to mammals and is required for induction of RNA polymerase II (pol II) transcription by DNA binding transcription factor.One of the proteins in this complex is MED28,also known as Magicin.MED28 is expressed in many cell lines and tissues.It has been shown that a down-regulation of MED28 expression in NIH3T3 cells results in a significant induction of several genes associated with smooth muscle cell differentiation and conversely its over-expression represses expression of SMC genes.MED28 can also form a ternary complex with Grb2 and Merlin,the neurofibromatosis 2 tumor suppressor protein,indicating that MED28 may play a role in Merlin's tumor suppressive activity.MED28 has also been recently identified as an HIV dependency factor (HDF),suggesting that MED28 may be an important drug target in HIV treatment.At least two isoforms of MED28 are known to exist. |
| Uniprot ID | Q9H204 |
| 基因名全称 | Mediator complex subunit 28 |
| 蛋白名全称 | Mediator complex subunit 28 |
| 推荐稀释比 | MED28 antibody can be used for detection of MED28 by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples and Immunohistochemistry in human samples.All other applications and species not yet tested. |
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