产品货号：
Z20542
中文名称：
MEFV抗体
英文名称：
Anti-MEFV Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MEFV Antibody |
| 指标别名 | FMF;Marenostrin;Mediterranean fever;MEF;MEFV;Pyrin;TRIM20 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,IHC,ICC/IF,FCM,ELISA |
| 基因名称 | MEFV |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Pyrin/MEFV recombinant protein (Position:Q463-D781). |
| 实际分子量 | 86KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | MEFV (Mediterranean fever) is a human gene that provides instructions for making a protein called pyrin (also known as marenostrin).Pyrin is produced in certain white blood cells (neutrophils,eosinophils and monocytes) that play a role in inflammation and in fighting infection.Inside these white blood cells,pyrin is found with thecytoskeleton,the structural framework that helps to define the shape,size,and movement of a cell.Pyrin's protein structure also allows it to interact with other molecules involved in fighting infection and in the inflammatory response.Although pyrin's function is not fully understood,it likely assists in keeping the inflammation process under control.Research indicates that pyrin helps regulate inflammation by interacting with the cytoskeleton.And Pyrin may direct the migration of white blood cells to sites of inflammation and stop or slow the inflammatory response when it is no longer needed. |
| Uniprot ID | O15553 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | MEFV innate immuity regulator,pyrin |
| 蛋白名全称 | Pyrin |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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