产品货号:
Z20532
中文名称:
MMP11抗体
英文名称:
Anti-MMP11 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-MMP11 Antibody |
指标别名 | matrix metallopeptidase 11;SL-3;ST3;STMY3;MMP11 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC |
基因名称 | MMP11 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human MMP11 (104-135aa RWEKTDLTYRILRFPWQLVQEQVRQTMAEALK),different from the related mouse and rat sequences by three amino acids. |
实际分子量 | 55KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Stromelysin-3 (SL-3) also known as matrix metalloproteinase-11 (MMP-11) is an enzyme that in humans is encoded by the MMP11 gene.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes,such as embryonic development,reproduction,and tissue remodeling,as well as in disease processes,such as arthritis and metastasis.Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.However,the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway.Also in contrast to other MMP's,this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. |
Uniprot ID | P24347 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
推荐稀释比 | Western blot(WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:50~400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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