产品货号:
Z20404
中文名称:
MICA抗体
英文名称:
Anti-MICA Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-MICA Antibody |
指标别名 | MIC A;MICA;PERB11.1 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | MICA |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | MICA antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human MICA.The immunogen is located within the last 50 amino acids of MICA. |
计算分子量 | 43kDa |
成分 | MICA Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | MICA Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | MICA antibody can be stored at 4℃ up to one year.Antibodies should not be exposed to prolonged high temperatures. |
背景资料 | Major histocompatibility complex (MHC) class I proteins are ubiquitously expressed and mediate the recognition of intracellular antigens by cytotoxic T cells.A related family,termed the MHC class I chain-related (MIC) proteins are recognized by NKG2D,a receptor on NK and T cells,and promote anti-tumor activity.MICA,a member of the MIC family,is widely expressed on many tumors,and it is the MICA/NKG2D interaction that is thought to stimulate the anti-tumor reactivity by T lymphocytes.Both MICA and MICB mRNA are widely expressed in normal tissues,with MICA being present in virtually every tissue except the nervous system,suggesting that MIC protein expression may only be one component of the anti-tumor activity of the immune system. |
Uniprot ID | Q29983 |
基因名全称 | MHC class I polypeptide-related sequence A |
蛋白名全称 | MHC class I polypeptide-related sequence A |
推荐稀释比 | MICA antibody can be used for detection of MICA by Western blot at 0.5 ~ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 10μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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