产品货号：
Z20386
中文名称：
MFN1抗体
英文名称：
Anti-MFN1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MFN1 Antibody |
| 指标别名 | Fzo homolog;hfzo1;hfzo2;MFN1;mitofusin 1;Transmembrane GTPase MFN1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC |
| 基因名称 | MFN1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | MFN1 antibody was raised against a 17 amino acid peptide near the amino terminus of human MFN1.The immunogen is located within amino acids 20 - 70 of MFN1. |
| 计算分子量 | 84kDa |
| 成分 | MFN1 antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | MFN1 antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Mitofusin 1 (MFN1) and the related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes (1,2).MFN1 and MFN2 form homotypic and heterotypic complexes and coordinately regulate mitochondrial fusion and are essential for embryonic development (3).When ectopically expressed,MFN1 inhibits the apoptosis-associated amino-terminal conformation change in the apoptotic protein Bax but not its mitochondrial translocation,indicating that MFN1 is involved in the regulating the activation of Bax on the outer mitochondrial membrane (4). |
| Uniprot ID | Q8IWA4 |
| 基因名全称 | Mitofusin 1 |
| 蛋白名全称 | Mitofusin 1 |
| 推荐稀释比 | MFN1 antibody can be used for detection of MFN1 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for Immunocytochemistry at 5μg/mL.Antibody validated:Western Blot in human samples and Immunocytochemistry in human samples.All other applications and species not yet tested. |
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