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所在位置:所有产品 > 抗体抗原 > 一抗 > MC4R抗体
MC4R抗体图片
产品货号:
Z20362
中文名称:
MC4R抗体
英文名称:
Anti-MC4R Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-MC4R Antibody
指标别名melanocortin 4 receptor;BMIQ20;MC4R
克隆性Polyclonal
检验物种human,mouse,rat
应用范围ELISA,WB,IHC,IF
基因名称MC4R
抗体来源Rabbit
抗体类型IgG
免疫原MC4R antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human MC4R.The immunogen is located within the first 50 amino acids of MC4R.
计算分子量37kDa
成分MC4R Antibody is supplied in PBS containing 0.02% sodium azide.
纯化方式MC4R Antibody is affinity chromatography purified via peptide column.
浓度1mg/mL
产品形态溶液
保存条件4℃可保存3个月,-20℃可保存1年。
背景资料The melanocortin-4 receptor (MC4R) is a member of the superfamily of seven transmembrane G-protein coupled receptors that are involved in multiple signal transduction pathways including the cAMP and MAPK signaling pathways.It is thought that the melanocortin system modulates energy expenditure and insulin sensitivity;activation of the MC4R results in the inhibition of c-Jun N-terminal kinase (JNK) activity and promotes insulin signaling.MC4R-null mice display maturity onset obesity characterized by hyperphagia,increased adiposity,hyperinsulinaemia and hyperleptinaemia,suggesting that like other obesity-linked genes such as FTO,PTER,and NPC1,MC4R is a potential candidate target for the treatment of obesity.
Uniprot IDP32245
基因名全称Melanocortin 4 receptor
蛋白名全称Melanocortin 4 receptor
推荐稀释比MC4R antibody can be used for detection of MC4R by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in rat samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested.

相关搜索:MC4R抗体MC4R多抗Anti-MC4R Antibody
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