产品货号:
Z20359
中文名称:
M-CSFR/CSF1R抗体
英文名称:
Anti-M-CSFR/CSF1R Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-M-CSFR/CSF1R Antibody |
指标别名 | C FMS;CD115;CSF 1 R;CSF1R;CSFR;FIM2;FMS;Proto oncogene c Fms |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB |
基因名称 | CSF1R |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human MCSF Receptor(955-972aa EQGDIAQPLLQPNNYQFC),different from the related mouse sequence by one amino acid and from the related rat sequence by two amino acids. |
实际分子量 | 108KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | CSF1R(Colony-Stimulating Factor 1 Receptor) also known as MCSFR,FMS,c-FMS,CD115,ONCOGENE FMS or CD115 ANTIGEN,encodes a tyrosine kinase growth factor receptor for colony-stimulating factor-1,the macrophage-and monocyte-specific growth factor.The gene is located on long arm of chromosome 5(5q32) on the Crick(minus) strand.The as-yet-unidentified°CSF1 Rpromoter/enhancer sequences may be confined to the nucleotides separating the 2 genes or could potentially lie within the PDGFR gene itself.The encoded protein is a single pass type I membrane protein and acts as the receptor for°Colony stimulating factor 1,a cytokine which controls the production,differentiation,and function of macrophages.The encoded protein is atyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases.Kondo et al.(2000) showed that the endogenous myelomonocytic cytokine receptors for GM-CSF and macrophage colony-stimulating factor(CSF1R) are expressed at low to moderate levels on the more primitive hematopoietic stem cells,are absent on common lymphoid progenitors,and are upregulated after myeloid lineage induction by IL2. |
Uniprot ID | P07333 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | Colony stimulating factor 1 receptor |
蛋白名全称 | Macrophage colony-stimulating factor 1 receptor |
推荐稀释比 | Western blot(WB) 1:500~2000 |
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