产品货号：
Z20349
中文名称：
MACC1抗体
英文名称：
Anti-MACC1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MACC1 Antibody |
| 指标别名 | 7A5,MACC1,SH3BP4L |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | MACC1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | MACC1 antibody was raised against a 17 amino acid synthetic peptide near the center of human MACC1.The immunogen is located within amino acids 430 - 480 of MACC1. |
| 计算分子量 | 97kDa |
| 成分 | MACC1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | MACC1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Metastasis associated in colon cancer 1 (MACC1) is a key regulator of the hepatocyte growth factor (HGF)-HGF receptor (MET) pathway,which is involved in cellular growth,epithelial-mesenchymal transition,angiogenesis,cell motility,invasiveness,and metastasis.MACC1 protein consists of four domains:ZU5,SH3,and two C-terminal death domains (DD).Expression of MACC1 was found significantly upregulated in malignant tissues (colon cancer of all stages as well as liver and lung metastases) compared to normal tissues or adenomas.MACC1 represents an early and crucial prognostic indicator for colon cancer metastasis that is independent of age,sex,tumor infiltration,nodal status,and lymph vessel invasion.Besides its involvement in signal transduction with the MET receptor,MACC1 also links MET signaling and apoptosis.MACC1 may also be an important therapeutic target for colorectal cancer treatment. |
| Uniprot ID | Q6ZN28 |
| 基因名全称 | Metastasis associated in colon cancer 1 |
| 蛋白名全称 | Metastasis associated in colon cancer 1 |
| 推荐稀释比 | MACC1 antibody can be used for detection of MACC1 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human and mouse samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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