产品货号：
Z20304
中文名称：
Klotho/KL抗体
英文名称：
Anti-Klotho/KL Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Klotho/KL Antibody |
| 指标别名 | KL;klotho |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | KL |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Anti-KLOTHO antibody was raised against a peptide corresponding to 17 amino acids near the center of human KLOTHO.The immunogen is located within amino acids 410-460 of KLOTHO. |
| 计算分子量 | 116kDa |
| 成分 | KLOTHO Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | KLOTHO Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | KLOTHO is the systemic anti-aging hormone within the glycosidase1 superfamily.It encodes a type I membrane protein that is abundant in the kidney and brain.In mice,a deficiency in KLOTHO expression leads to various systemic phenotypes resembling human aging such as arteriosclerosis,osteoporosis,and skin atrophy together with growth retardation,short life-span and infertility.Transgenic mice overexpressing KLOTHO have an extended life span by inhibiting insulin/IGF1 signaling.KLOTHO is involved in the regulation of calcium/phosphorus homeostasis by inhibiting the synthesis of active vitamin D and identified as a potential tumor suppressor. |
| Uniprot ID | Q9UEF7 |
| 基因名全称 | Klotho |
| 蛋白名全称 | Klotho |
| 推荐稀释比 | WB:1～4μg/mL;IHC:2.5μg/mL;IF:20μg/mL.Antibody validated:Western Blot in human,mouse and rat samples;Immunohistochemistry in mouse and rat samples;Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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