产品货号:
Z20248
中文名称:
MBNL1抗体
英文名称:
Anti-MBNL1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
| 抗体名称 | Anti-MBNL1 Antibody |
| 指标别名 | muscleblind like splicing regulator 1;EXP;MBNL;MBNL1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat,monkey |
| 应用范围 | WB,IHC,IF,ICC/IF,ELISA |
| 基因名称 | MBNL1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human MBNL1 recombinant protein (Position:Q89-M388). |
| 计算分子量 | 42KD |
| 实际分子量 | 40KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Muscleblind-like (Drosophila),also known as MBNL1,is a protein that in humans is encoded by the MBNL1 gene.It is mapped to 3q25.1-q25.2.This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster.The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs.Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy.Mice lacking this gene exhibited muscle abnormalities and cataracts.Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined.The different isoforms are thought to have different binding specificities and/or splicing activities. |
| Uniprot ID | Q9NR56 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 基因名全称 | muscleblind like splicing regulator 1 |
| 蛋白名全称 | Muscleblind-like protein 1 |
| 推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:50~400 Immunofluorescence (IF) 1:50~400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50~400 ELISA: 1:100~1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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