产品货号：
Z20181
中文名称：
MAP3K8抗体
英文名称：
Anti-MAP3K8 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MAP3K8 Antibody |
| 指标别名 | mitogen-activated protein kinase kinase kinase 8;AURA2;COT;EST;ESTF;MEKK8;TPL2;Tpl-2;c-COT;MAP3K8 |
| 克隆性 | Polyclonal |
| 检验物种 | human,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | MAP3K8 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human MAP3K8 recombinant protein (Position:D9-L193).Human MAP3K8 shares 89.7% and 90.3% amino acid (aa) sequence identity with mouse and rat MAP3K8,respectively. |
| 实际分子量 | 53KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Mitogen-activated protein kinase kinase kinase 8 is an enzyme that in humans is encoded by the MAP3K8 gene.This gene is an oncogene that encodes a member of the serine/threonine protein kinase family.The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways.This protein was shown to activate IkappaB kinases,and thus induce the nuclear production of NF-kappaB.Additionally,this protein was found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation.This gene may also utilize a downstream in-frame translation start codon,and thus produce an isoform containing a shorter N-terminus.The shorter isoform has been shown to display weaker transforming activity.Alternate splicing results in multiple transcript variants that encode the same protein. |
| Uniprot ID | P41279 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | mitogen-activated protein kinase kinase kinase 8 |
| 蛋白名全称 | Mitogen-activated protein kinase kinase kinase 8 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 23 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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