产品货号:
Z20175
中文名称:
MAP1/MOAP1抗体
英文名称:
Anti-MAP1/MOAP1 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
| 抗体名称 | Anti-MAP1/MOAP1 Antibody |
| 指标别名 | MAP-1;PNMA4;Modulator of apoptosis 1;Paraneoplastic antigen Ma4;MAP-1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB |
| 基因名称 | MOAP1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | MAP-1 antibody was raised against a 15 amino acid synthetic peptide from near the center of human MAP-1.The immunogen is located within the last 50 amino acids of MAP1. |
| 计算分子量 | 40kDa |
| 成分 | MAP1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | MAP1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
| 背景资料 | Apoptosis plays a major role in normal organism development,tissue homeostasis,and removal of damaged cells.Disruption of this process has been implicated in a variety of diseases such as cancer.Members of the Bcl-2 family are known to be critical regulators of this process.These proteins are characterized by the presence of several conserved motifs termed Bcl-2 homology (BH) domains.A related protein termed MAP-1 has recently been identified.This protein contains a BH3-like domain and induces caspase-dependent apoptosis in mammalian cells when overexpressed.It forms homodimers and associates with Bcl-2 family members such as Bax,Bcl-2,and Bcl-XL in vitro and in vivo.It has been suggested that MAP-1 associates with the tumor suppressor RASSF1A following death receptor activation,allowing a conformational change in Bax that leads to cellular apoptosis. |
| Uniprot ID | Q96BY2 |
| 基因名全称 | Modulator of apoptosis 1 |
| 蛋白名全称 | Modulator of apoptosis 1 |
| 推荐稀释比 | MAP1 antibody can be used for the detection of MAP-1 by Western blot at 1 to 4μg/mL.Antibody validated:Western Blot in mouse samples.All other applications and species not yet tested. |
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