产品货号:
Z20125
中文名称:
MED12抗体
英文名称:
Anti-MED12 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-MED12 Antibody |
指标别名 | MED12;ARC240;CAGH45;HOPA;KIAA0192;TNRC11;TRAP230;Mediator of RNA polymerase II transcription subunit 12;Activator-recruited cofactor 240kDa component;ARC240;CAG repeat protein 45;Mediator complex subunit 12;OPA-containing protein;Thyroid hormone receptor-associated protein complex 230kDa component;Trap230;Trinucleotide repeat-containing gene 11 protein |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB,ELISA |
基因名称 | MED12 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human MED12 recombinant protein (Position:Q752-Q1974). |
实际分子量 | 260KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Mediator of RNA polymerase II transcription,subunit 12 homolog (S.cerevisiae),also known as MED12,is a human gene found on the X chromosome.The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex.A component of this preinitiation complex is a 1.2 MDa protein aggregate called Mediator.This Mediator component binds with a CDK8 subcomplex which contains the protein encoded by this gene,mediator complex subunit 12 (MED12),along with MED13,CDK8 kinase,and cyclin C.The CDK8 subcomplex modulates Mediator-polymerase II interactions and thereby regulates transcription initiation and reinitation rates.The MED12 protein is essential for activating CDK8 kinase.Defects in this gene cause X-linked Opitz-Kaveggia syndrome,also known as FG syndrome,and Lujan-Fryns syndrome. |
Uniprot ID | Q93074 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
基因名全称 | mediator complex subunit 12 |
蛋白名全称 | Mediator of RNA polymerase II transcription subunit 12 |
推荐稀释比 | Western blot (WB) 1:500~2000 ELISA 1:100~1000 |
Gene ID | 9968 |
相关搜索:MED12抗体,MED12多抗,Anti-MED12 Antibody