产品货号：
Z20122
中文名称：
MECP2抗体
英文名称：
Anti-MECP2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MECP2 Antibody |
| 指标别名 | AUTSX3;MeCp 2 protein;MECP2;Methyl CpG binding protein 2;MRX16;MRX79;MRXS13;MRXSL;PPMX;RTS;RTT |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,ELISA |
| 基因名称 | MECP2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human MECP2 recombinant protein (Position:K119-R453). |
| 实际分子量 | 75KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | MECP2 (methyl CpG binding protein 2) is a gene that encodes the protein MECP2.It is mapped to Xq28.DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development.Human proteins MECP2,MBD1,MBD2,MBD3,and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD).Each of these proteins,with the exception of MBD3,is capable of binding specifically to methylated DNA.MECP2,MBD1 and MBD2 can also repress transcription from methylated gene promoters.In contrast to other MBD family members,MECP2 is X-linked and subject to X inactivation.MECP2 is dispensible in stem cells,but is essential for embryonic development.MECP2 gene mutations are the cause of most cases of Rett syndrome,a progressive neurologic developmental disorder and one of the most common causes of cognitive disability in females.Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Uniprot ID | P51608 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry in fixed cells 1:50～400 (ELISA)： 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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