
产品货号:
Z19987
中文名称:
MAD2L2抗体
英文名称:
Anti-MAD2L2 Antibody (C-term)
产品规格:
80μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-MAD2L2 Antibody (C-term) |
指标别名 | hREV7;MAD2 like protein 2;MAD2B;MAD2L2;REV7;REV7 homolog |
克隆性 | Polyclonal |
检验物种 | mouse |
应用范围 | IF,IHC,WB |
基因名称 | MAD2L2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | This MAD2L2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 198-231 amino acids from the C-terminal region of human MAD2L2. |
计算分子量 | 24kDa |
成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
保存条件 | Maintain refrigerated at 2~8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
背景资料 | Adapter protein able to interact with different proteins and involved in different biological processes.Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1,thereby mediating the second polymerase switching in translesion DNA synthesis.Translesion DNA synthesis releases the replication blockade of replicative polymerases,stalled in presence of DNA lesions.May also regulate another aspect of cellular response to DNA damage through regulation of the JNK-mediated phosphorylation and activation of the transcriptional activator ELK1.Inhibits the FZR1- and probably CDC20-mediated activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle.Regulates TCF7L2-mediated gene transcription and may play a role in epithelial-mesenchymal transdifferentiation. |
Uniprot ID | Q9UI95 |
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