产品货号：
Z19980
中文名称：
LRRK2抗体
英文名称：
Anti-LRRK2 Antibody (C-term)
产品规格：
80μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-LRRK2 Antibody (C-term) |
| 指标别名 | leucine rich repeat kinase 2;AURA17;DARDARIN;PARK8;RIPK7;ROCO2;LRRK2 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,FCM |
| 基因名称 | LRRK2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This LRRK2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2171-2207 amino acids from the C-terminal region of human LRRK2. |
| 计算分子量 | 286kDa |
| 成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | Positively regulates autophagy through a calcium- dependent activation of the CaMKK/AMPK signaling pathway.The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors,increase in lysosomal pH,and calcium release from lysosomes.Together with RAB29,plays a role in the retrograde trafficking pathway for recycling proteins,such as mannose 6 phosphate receptor (M6PR),between lysosomes and the Golgi apparatus in a retromer-dependent manner.Regulates neuronal process morphology in the intact central nervous system (CNS).Phosphorylates PRDX3.May also have GTPase activity.May play a role in the phosphorylation of proteins central to Parkinson disease. |
| Uniprot ID | Q5S007 |
相关搜索：LRRK2抗体，LRRK2(C-term)多抗，Anti-LRRK2 Antibody (C-term)