产品货号：
Z19774
中文名称：
LIN41/TRIM71抗体
英文名称：
Anti-LIN41/TRIM71 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-LIN41/TRIM71 Antibody |
| 指标别名 | LIN 41;LIN41;Protein lin 41 homolog;TRIM71;tripartite motif containing 71 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | TRIM71 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | TRIM71 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human TRIM71.The immunogen is located within amino acids 680 - 730 of TRIM71. |
| 计算分子量 | 93kDa |
| 成分 | TRIM71 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | TRIM71 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | TRIM71 is the mammalian ortholog to the C.elegans heterochronic protein Lin41,a protein that is thought to be important in postembryonic development,and is genetically and biochemically downstream of both Shh and Fgf signaling pathways.Similar to its C.elegans homolog,TRIM71 is a target of the microRNA let-7 and is likely to play a role in mammalian development.Recent experiments have indicated that TRIM71 is an E3 ubiquitin ligase and can interact with the Dicer and the Argonaute proteins Ago1,Ago2,and Ago4.Overexpression and depletion of TRIM71 led to inverse changes in Ago2 protein levels,suggesting TRIM71 can regulate Ago2 turnover.Finally,TRIM71 cooperates with the pluripotency factor Lin-28 in regulating let-7. |
| Uniprot ID | Q2Q1W2 |
| 基因名全称 | Tripartite motif-containing 71 |
| 蛋白名全称 | Tripartite motif-containing 71 |
| 推荐稀释比 | TRIM71 antibody can be used for detection of TRIM71 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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